Tying rings for sex.
نویسندگان
چکیده
The primary component of the sex pilus encoded by IncP (RP4) and Ti plasmids has been identified as a circular pilin protein with a peptide bond between the amino and carboxyl terminus. Here, we review the key experiments that led to this discovery, and the present mechanistic model for pilin-precursor processing and the cyclization reaction. In addition, we discuss the implications for horizontal gene transfer in bacterial conjugation.
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ورودعنوان ژورنال:
- Trends in microbiology
دوره 10 8 شماره
صفحات -
تاریخ انتشار 2002